Diabetes

Vitamin D deficiency occurs in type 1 diabetes already at an early stage

Vitamin D "early supplement"?

Low vitamin D levels are a frequent accompanying phenomenon in type 1 diabetes. But even children who show more positive autoantibodies without overt diabetes, which is a precursor of type 1 diabetes have decreased vitamin D levels in the blood. In the course of the disease - from a prediabetes towards diabetes - this tendency is, however, not affecting, scientists of the Helmholtz Zentrum München and the Technische Universität München in the scientific journal, Diabetologia '.

Vitamin D is known as an important regulator of calcium balance and bone metabolism. In addition, it also affects the immune system. Previous studies have shown that when patients present with newly diagnosed type-1 diabetes significantly reduced vitamin D levels. The scientists from the Diabetes Research Institute (IDF), the Helmholtz Zentrum München, a partner at the German Center for Diabetes Research (DZD) and the Diabetes Research Group at the Technical University of Munich (TUM) have now been exploring the question of whether a vitamin D deficiency already in precursors of diabetes, defined by the presence of several diabetes-specific autoantibodies, occurs and how far the disease progression is affected by it.

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Weight loss through diabetes medications?

It depends on the effect in the brain

It was previously unclear why taking certain diabetes medications in some patients leads to reduced appetite and weight loss, but in others not. A date in the journal "Diabetes Care" published Leipzig study showed that the weight-reducing effect of the so-called GLP-1 analogues occurs when a certain region of the brain called the hypothalamus, particularly strongly interacts with other brain regions.

 

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Stevia is not healthier than other sugar substitutes

The sweetener stevia is not better or worse than other sugar substitutes suitable for diabetic patients. This is indicated by the German Diabetes Association (DDG). "Stevia is another alternative to sugar, which receives no calories," explains Professor Dr. med. Stephan Matthaei, President of the DDG. "No more and no less."

Since the removal of diabetic products from the market applies that all healthy foods are basically equally suitable for diabetic patients as for non-diabetic patients. Only for people who suffer from phenylketonuria of the congenital metabolic disorder but need sweeteners, stevia is a good alternative, so Matthaei.

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Hormones in the double against fat and diabetes

 

The interplay of the hormones glucagon and fibroblast growth factor 21 (FGF21) regulates vital lipid metabolism and body weight. Their combined effect results in a decreased food intake and increased fat burning, so the messengers are considered as promising candidates for the treatment of obesity and type diabetes 2. This found scientists from the Institute for Diabetes and Obesity (IDO), Helmholtz Zentrum München in collaboration with the Metabolic Diseases Institute at the University of Cincinnati, USA, out. The results were published in the current issue of the journal, Diabetes'.

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Good bacteria in the gut bow diabetes before

Diabetes type 1, which occurs more frequently, especially in young people, can possibly be stopped by intestinal bacteria. This has found an international group of researchers with participation Berner.

People have almost endless many bacteria in the lower intestine - about 100 trillion (10 14 high). In order for our body contains more bacteria than 10mal body cells - and these tiny organisms are important for our health. They help us digest food and provide us with energy and vitamins.

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Diabetes increase can not be explained solely with obesity

Since 1998 the number of obese people in Germany as a whole is unchanged, the increased of obese men and women easily. In the same period there was a significant increase of diseases with Type 2 diabetes mellitus, as a recent study by the Robert Koch Institute shows. This diabetes increase does not correspond to more obese people in our society, notes the German Diabetes Association (DDG).

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Anti-stress program helps diabetics

First results of the Heidelberg diabetes and stress-study (Heidi) prove positive effect on dealing with disease and Psyche / influence on renal function is not to assess

Diabetics who better relax by an "anti-stress training" and learn the mental approach to their disease, have long-term may be less damage to health and psychological problems. This is the result Heidelberger Diabetes and Stress study comes (Heidi), the first controlled clinical trial that examined the effect of stress reduction in diabetics. Your results after one year therapy have now been published: The participants in the eight-week anti-stress group therapy with weekly exercise program were less depressed and physically fitter after one year, for example, had lower blood pressure. However, it was their protein excretion, which increases with decreasing kidney function, unchanged - in the untreated control group, these had continued to deteriorate.

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Liver regulates hunger

Researchers at the University of Melbourne and the largest Australian health provider Austin Health are the secret on the track how our body regulates fat balance and weight. Together with Professor Sof Andrikopolous has found that the liver directly communicates with our brain to control the food amount that we consume daily are those governing Austin Health in Melbourne Barbara Fam.

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Diabetes: How sugar leads to pain

Many diabetic people suffering from chronic pain, especially in the calves and feet. The mechanism of diabetic nerve disease, scientists have I and Clinical Chemistry at the University Hospital Heidelberg, now enlightened by Professor Dr. Angelika Bierhaus and Professor Dr. Peter P. Nawroth, medical director of Abeilung Internal Medicine: The metabolite methylglyoxal, which in the breakdown of sugars blood arises, binds to pain-conducting nerve cells and makes them hypersensitive. Here there is a threshold for the sensation of pain. For the first time a treatment approach was identified which acts directly on the release of the pain and not to the nervous system: In animals lowered agents intercepted the methylglyoxal, the strong sensation of pain. The scientific studies were supported by the Dietmar Hopp Foundation, St. Leon-Rot; their results have been 13. May 2012 published in the renowned journal "Nature Medicine".

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Diabetes drug inhibits dangerous inflammation of the adipose tissue

The abdominal fat tissue of obese people is chronically inflamed. This is considered a major cause for the development of diabetes type 2. In normal weight mice a specific group of immune cells holds this inflammation at bay. Scientists of the German Cancer Research Center and Harvard Medical School have now published in Nature that, these immune cells activate a diabetes drug. The activated immune cells not only curb the dangerous inflammation, but also ensure that normal sugar metabolism.

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Every Step Counts: idleness can enhance diabetes consequences yet

Study of sports medicine at the University of Münster showed: Patients with peripheral neuropathy move far too little

Affected describe it as tingling, pricking, or numbness in the feet. From peripheral neuropathy between ten and 20 percent of all diabetics are affected. The cause: The permanently increased blood sugar levels the sensation nerves are damaged. Movement is known to be an ideal means to reduce glucose in the blood. "But the more severe their symptoms, the more inactive the patients," laments Prof. Dr. Klaus peoples, Director of the Institute for Sports Medicine at the University of Münster. His finding is based on a recently completed at the Institute study.

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